Using Bioinformatic Tools to Uncover that Protein 2fr2 May Function in Detoxification of Reactive Nitrogenous Molecules
Location
CoLab, COM 271
Start Date
30-4-2026 1:15 PM
Document Type
Poster
Description
Scientists have documented the sequence and structure of thousands of proteins for which the identification and biological function remain unknown. Any number of these unknown proteins could be the key to unlocking new avenues for drug development and disease research. This research will involve searching the sequence and structure of an unknown protein, 2fr2, in databases such as Interpro, BLAST, CLEAN, and FoldSeek, for proteins with similar sequence or shape, and to use information known about the functions of those proteins to inform further research on the unknown protein. Bioinformatic analysis revealed that the unknown protein 2fr2 may be related to the peroxynitrite isomerase family, the nitrobindin family, or the spirocyclase family. All these pieces of information provide avenues to further explore the function of the 2fr2 protein.
Image
Using Bioinformatic Tools to Uncover that Protein 2fr2 May Function in Detoxification of Reactive Nitrogenous Molecules
CoLab, COM 271
Scientists have documented the sequence and structure of thousands of proteins for which the identification and biological function remain unknown. Any number of these unknown proteins could be the key to unlocking new avenues for drug development and disease research. This research will involve searching the sequence and structure of an unknown protein, 2fr2, in databases such as Interpro, BLAST, CLEAN, and FoldSeek, for proteins with similar sequence or shape, and to use information known about the functions of those proteins to inform further research on the unknown protein. Bioinformatic analysis revealed that the unknown protein 2fr2 may be related to the peroxynitrite isomerase family, the nitrobindin family, or the spirocyclase family. All these pieces of information provide avenues to further explore the function of the 2fr2 protein.
Comments
The faculty mentor for this project was Faith Jacobsen.