Start Date
27-4-2023 9:00 AM
Document Type
Poster
Description
Since the discovery of penicillin by Alexander Fleming in 1928, more and more antibiotics had been discovered and developed. Antibiotics have been the cure of almost all the bacterial infections and disease. Scientists and researchers would collect samples from various locations, grow the microbes, and carefully examine them. Those successfully discovered microbes had played a huge role as antibiotics. However, recently we are in what it’s called the “post antibiotic era.” Like a child learning and adapting to their environment as they grow, researchers discovered that microbes also are capable of adapting to their surrounding environment. Therefore, the more pathogenic bacteria are exposed to antibiotics, the less effective the antibiotics will become to the pathogenic bacteria. Because of that, this research was done to contribute to discovering a candidate that can be a possible new antibiotic. From the 12 candidates I have collected from the soil sample of mine, I found the best possible candidate throughout the careful examination, which is named Matthew. He has inhibited Acinetobacter baylyi, Pseudomonas putida, Escherichia coli, Enterococcus faecalis, Staphylococcus epidermidis, Bacillus subtilis, and Mycobacterium smegmatis.
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Discovery of "Matthew," The Possible Hero in the "Post" Antibiotic Era
Since the discovery of penicillin by Alexander Fleming in 1928, more and more antibiotics had been discovered and developed. Antibiotics have been the cure of almost all the bacterial infections and disease. Scientists and researchers would collect samples from various locations, grow the microbes, and carefully examine them. Those successfully discovered microbes had played a huge role as antibiotics. However, recently we are in what it’s called the “post antibiotic era.” Like a child learning and adapting to their environment as they grow, researchers discovered that microbes also are capable of adapting to their surrounding environment. Therefore, the more pathogenic bacteria are exposed to antibiotics, the less effective the antibiotics will become to the pathogenic bacteria. Because of that, this research was done to contribute to discovering a candidate that can be a possible new antibiotic. From the 12 candidates I have collected from the soil sample of mine, I found the best possible candidate throughout the careful examination, which is named Matthew. He has inhibited Acinetobacter baylyi, Pseudomonas putida, Escherichia coli, Enterococcus faecalis, Staphylococcus epidermidis, Bacillus subtilis, and Mycobacterium smegmatis.
Comments
The faculty mentor for this project was Jamie Cunningham, Biology.