Antibiotic Candidate Testing

Location

CoLab, OCB 100

Start Date

27-4-2018 9:00 AM

Document Type

Poster

Description

Antibiotic resistance is when drugs are made less effective due to bacterial changes. This is a rising issue and not very many big pharmaceutical companies are putting any effort towards this issue. It is important to conduct research to find possible new sources for antibiotics, so that we don’t run into issues where we do not have the medicine to treat infectious disease. I have collected a soil sample and have diluted that sample. I have chosen to collect a soil sample because there has been other samples collected that have proven to contain antibiotic candidates. From there I have isolated potential candidates. These candidates have been tested with the 5 lab safe ESKAPE pathogens. If a bacterium can inhibit growth, then it is classified as an antibiotic-producing candidate. I identified a candidate bacterium that is yellow, irregular, and flat in appearance. I will present my findings to characterize and identify this candidate by using staining, sequencing, and other forms of testing. More testing will be conducted on this bacteria, which will provide more information on the poster. I hope this information helps guide future tests with information regarding techniques and the outcomes from those techniques.

Comments

The faculty supervisor for this project was Jon Kniss, Biology.

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Apr 27th, 9:00 AM

Antibiotic Candidate Testing

CoLab, OCB 100

Antibiotic resistance is when drugs are made less effective due to bacterial changes. This is a rising issue and not very many big pharmaceutical companies are putting any effort towards this issue. It is important to conduct research to find possible new sources for antibiotics, so that we don’t run into issues where we do not have the medicine to treat infectious disease. I have collected a soil sample and have diluted that sample. I have chosen to collect a soil sample because there has been other samples collected that have proven to contain antibiotic candidates. From there I have isolated potential candidates. These candidates have been tested with the 5 lab safe ESKAPE pathogens. If a bacterium can inhibit growth, then it is classified as an antibiotic-producing candidate. I identified a candidate bacterium that is yellow, irregular, and flat in appearance. I will present my findings to characterize and identify this candidate by using staining, sequencing, and other forms of testing. More testing will be conducted on this bacteria, which will provide more information on the poster. I hope this information helps guide future tests with information regarding techniques and the outcomes from those techniques.