Towards the Isolation and Identification of Antimicrobial Compounds Produced by Lysinibacillus pakistanensis.
Location
CoLab, OCB 100
Start Date
28-4-2017 11:00 AM
End Date
28-4-2017 12:45 PM
Document Type
Poster
Description
Lysinibacillus pakistanensis has been reported to be useful in biodegrading hexavalent chromium, a harmful carcinogenic waste produced by leather industries. It was previously shown to inhibit the growth of E. faecalis, E. coli, A. faecalis, and P. aeruginosa when grown competitively using a cross streak method. Organic extracts from Lysinibacillus pakistanensis showed inhibition towards S. epidermidis and E. aerogenes in subsequent bioassays using TLC–bioautography. Further work to separate the components in the extract mixture and isolate the antimicrobial compound using both column chromatography and TLC will be discussed.
Image
Towards the Isolation and Identification of Antimicrobial Compounds Produced by Lysinibacillus pakistanensis.
CoLab, OCB 100
Lysinibacillus pakistanensis has been reported to be useful in biodegrading hexavalent chromium, a harmful carcinogenic waste produced by leather industries. It was previously shown to inhibit the growth of E. faecalis, E. coli, A. faecalis, and P. aeruginosa when grown competitively using a cross streak method. Organic extracts from Lysinibacillus pakistanensis showed inhibition towards S. epidermidis and E. aerogenes in subsequent bioassays using TLC–bioautography. Further work to separate the components in the extract mixture and isolate the antimicrobial compound using both column chromatography and TLC will be discussed.
Comments
The faculty supervisor for this project is Melanie Harvey, Chemistry.