Location
CoLab, COM 100
Start Date
1-5-2025 5:30 PM
Document Type
Poster
Description
Polypeptides, being the building blocks of proteins, are a crucial part to many biological systems. The goal in this experiment was to protect and deprotect an amino acid and eventually make a tripeptide using poly peptide synthesis. The amino acid used was L-valine which had to go through a protection reaction where BOC was added to protect the NH2 group on the L-valine. This has to be done so the amino acid can be resistant in more basic conditions. L-valine then has to go through a deprotection reaction to then remove the BOC group and isolate the amino acid. After a tripeptide is made it is tested to see if it can inhibit any bacterial growth, this will show how effective it would be as antibiotics antibiotic.
Image
Assessing Tripeptide Efficacy as Antibiotic Agents
CoLab, COM 100
Polypeptides, being the building blocks of proteins, are a crucial part to many biological systems. The goal in this experiment was to protect and deprotect an amino acid and eventually make a tripeptide using poly peptide synthesis. The amino acid used was L-valine which had to go through a protection reaction where BOC was added to protect the NH2 group on the L-valine. This has to be done so the amino acid can be resistant in more basic conditions. L-valine then has to go through a deprotection reaction to then remove the BOC group and isolate the amino acid. After a tripeptide is made it is tested to see if it can inhibit any bacterial growth, this will show how effective it would be as antibiotics antibiotic.
Comments
The faculty mentor for this project was Meagan Weldele, Chemistry.