Start Date
27-4-2023 12:00 PM
Document Type
Poster
Description
Science academics have long considered genes and mutation to be essential subjects. A mutation is a change in the DNA sequence affecting a gene's physical structure and function. Genetic diseases are closely related to protein mutation. Hence, to maintain well-balanced human health, and normal body function, it is essential to comprehend the significance of mutation and handle the change in DNA sequence. The development of technology has made it possible for us to undertake studies and learn about the role of enzymes in human life. In this study, I perform laboratory experiments to modify an amino acid and compare the results to initial data collected from Fold It software. The selected amino acid changes from asparagine N293 to methionine M and anticipates to experience a decline in stability. Beta-glucosidase B would be employed as an enzyme model in this investigation. Upon completing the project, I am contributing to the information-gathering process that will improve artificial intelligence and advance science.
Image
Attention to Oligonucleotide‐directed Mutagenesis
Science academics have long considered genes and mutation to be essential subjects. A mutation is a change in the DNA sequence affecting a gene's physical structure and function. Genetic diseases are closely related to protein mutation. Hence, to maintain well-balanced human health, and normal body function, it is essential to comprehend the significance of mutation and handle the change in DNA sequence. The development of technology has made it possible for us to undertake studies and learn about the role of enzymes in human life. In this study, I perform laboratory experiments to modify an amino acid and compare the results to initial data collected from Fold It software. The selected amino acid changes from asparagine N293 to methionine M and anticipates to experience a decline in stability. Beta-glucosidase B would be employed as an enzyme model in this investigation. Upon completing the project, I am contributing to the information-gathering process that will improve artificial intelligence and advance science.
Comments
The faculty mentor for this project was Heather Seitz, Biology.