Start Date
27-4-2023 10:30 AM
Document Type
Poster
Description
The purpose of this research is to identify potential new antibiotics from soil samples. Antibiotic resistant microbes are a community health risk. Microbes are becoming resistant to antibiotics faster than we can develop new drugs to treat them with. In partnership with Tiny Earth Network, we are crowdsourcing potential new antibiotics with this research on soil samples. To this end, a soil sample was collected from my front yard and potential candidates were isolated for subsequent microbial screening. Initially 12 candidates were chosen and screened against 8 pathogens, E. coli, A.baylyi, P. putida, S. epidermidis, E. faecallis, E. aerogenes, M. smegmatis, and B. subtilis. While several candidates showed promise against one or two organisms a single candidate showed promise against 7 of the 8 pathogens. This microbe shows exceptional zones of inhibition against the screened pathogens. This microbe is identified as 5B, further research will be done to determine just how helpful this microbe can be in the pursuit of novel antibiotics. Join me as we discover what this microbe has to show us.
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Microbes in My Neighborhood, The Hunt for New Antibiotics in Soil
The purpose of this research is to identify potential new antibiotics from soil samples. Antibiotic resistant microbes are a community health risk. Microbes are becoming resistant to antibiotics faster than we can develop new drugs to treat them with. In partnership with Tiny Earth Network, we are crowdsourcing potential new antibiotics with this research on soil samples. To this end, a soil sample was collected from my front yard and potential candidates were isolated for subsequent microbial screening. Initially 12 candidates were chosen and screened against 8 pathogens, E. coli, A.baylyi, P. putida, S. epidermidis, E. faecallis, E. aerogenes, M. smegmatis, and B. subtilis. While several candidates showed promise against one or two organisms a single candidate showed promise against 7 of the 8 pathogens. This microbe shows exceptional zones of inhibition against the screened pathogens. This microbe is identified as 5B, further research will be done to determine just how helpful this microbe can be in the pursuit of novel antibiotics. Join me as we discover what this microbe has to show us.
Comments
The faculty mentor for this project was Jamie Cunningham, Biology.