Location

OCB 100

Start Date

28-4-2022 9:00 AM

Document Type

Poster

Description

Infectious disease was historically a leading cause of death of death for humans until we discovered and harnessed the power of the antibiotic properties of microbes. However, the overuse of known antibiotics and the ability of pathogenic organisms to continually evolve has led us to a critical point. The rise of antibiotic resistant pathogens poses a great risk to future generations, and it is imperative that we find new and novel sources of these life-saving medications. In service to the Tiny Earth Network's mission to crowd-source novel antibiotics from soil microbes, this investigation examined some of the smallest residents of Fairfield Farm in Lawson, MO. From the septic field to its isolation in the lab of SCI 113, DYER012 2-2 has shown antibiotic properties against five of the six ESKAPE pathogens. This Gram-negative, non-spore forming, bacillus will have undergone PCR, Gel Electrophoresis, DNA sequencing, and several other tests in the quest to reveal its identity at this Symposium. It is my hope that this work regarding the identity and characteristics DYER012 2-2 will contribute meaningfully to the global fight against antibiotic resistant pathogens.

Comments

The faculty mentor for this project was Angela Consani, Biology.

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Apr 28th, 9:00 AM

Tiny Earth Exploration of Fairfield Farm

OCB 100

Infectious disease was historically a leading cause of death of death for humans until we discovered and harnessed the power of the antibiotic properties of microbes. However, the overuse of known antibiotics and the ability of pathogenic organisms to continually evolve has led us to a critical point. The rise of antibiotic resistant pathogens poses a great risk to future generations, and it is imperative that we find new and novel sources of these life-saving medications. In service to the Tiny Earth Network's mission to crowd-source novel antibiotics from soil microbes, this investigation examined some of the smallest residents of Fairfield Farm in Lawson, MO. From the septic field to its isolation in the lab of SCI 113, DYER012 2-2 has shown antibiotic properties against five of the six ESKAPE pathogens. This Gram-negative, non-spore forming, bacillus will have undergone PCR, Gel Electrophoresis, DNA sequencing, and several other tests in the quest to reveal its identity at this Symposium. It is my hope that this work regarding the identity and characteristics DYER012 2-2 will contribute meaningfully to the global fight against antibiotic resistant pathogens.