Isolation and Testing of Antimicrobial Compounds Produced by Bacteria Closely Related to Bacillus subtilis
Location
CoLab, OCB 100
Start Date
27-4-2018 9:00 AM
Document Type
Poster
Description
Bacillus subtilis has been widely used by biotechnology companies for industrial-scale secreted enzyme production. A close relative of Bacillus subtilis isolated from local soil samples was previously shown to inhibit the growth of E. coli and S. epidermidis when grown competitively using a cross streak method. Organic extracts from this bacteria has been tested against several ESKAPE pathogens using both direct application and TLC–bioautography. Further work to isolate and test the antimicrobial compounds produced by this bacteria closely related to Bacillus subtilis will be discussed.
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Isolation and Testing of Antimicrobial Compounds Produced by Bacteria Closely Related to Bacillus subtilis
CoLab, OCB 100
Bacillus subtilis has been widely used by biotechnology companies for industrial-scale secreted enzyme production. A close relative of Bacillus subtilis isolated from local soil samples was previously shown to inhibit the growth of E. coli and S. epidermidis when grown competitively using a cross streak method. Organic extracts from this bacteria has been tested against several ESKAPE pathogens using both direct application and TLC–bioautography. Further work to isolate and test the antimicrobial compounds produced by this bacteria closely related to Bacillus subtilis will be discussed.
Comments
The faculty supervisor for this project was Melanie Harvey, Chemistry.