Towards the Isolation and Identification of Antimicrobial Compounds Produced by Curtobacterium oceanosedimentum and the Initial Screening of Compounds Isolated from Paenibacillus polymyxa.
Location
CoLab, OCB 100
Start Date
28-4-2017 11:00 AM
End Date
28-4-2017 12:45 PM
Document Type
Poster
Description
Curtobacterium oceanosedimentum has been reported to exhibit a range of antimicrobial properties, including the inhibition of several gram-negative and gram-positive bacteria. It was previously shown to inhibit the growth of S. epidermidis when grown competitively using a cross streak method. Organic extracts from Curtobacterium oceanosedimentum showed inhibition towards S. epidermidis in subsequent bioassays using TLC–bioautography. Further work to separate the components in the extract mixture and isolate the antimicrobial compound using both column chromatography and TLC will be discussed. Paenibacillus polymyxa, often used for promotive plant growth in agricultural settings, was previously shown to inhibit the growth of E. aerogenes, S. epidermidis, and P. aeruginosa when grown competitively using a cross streak method. Results from TLC-bioautography of the organic extract from Paenibacillus polymyxa will also be discussed.
Image
Towards the Isolation and Identification of Antimicrobial Compounds Produced by Curtobacterium oceanosedimentum and the Initial Screening of Compounds Isolated from Paenibacillus polymyxa.
CoLab, OCB 100
Curtobacterium oceanosedimentum has been reported to exhibit a range of antimicrobial properties, including the inhibition of several gram-negative and gram-positive bacteria. It was previously shown to inhibit the growth of S. epidermidis when grown competitively using a cross streak method. Organic extracts from Curtobacterium oceanosedimentum showed inhibition towards S. epidermidis in subsequent bioassays using TLC–bioautography. Further work to separate the components in the extract mixture and isolate the antimicrobial compound using both column chromatography and TLC will be discussed. Paenibacillus polymyxa, often used for promotive plant growth in agricultural settings, was previously shown to inhibit the growth of E. aerogenes, S. epidermidis, and P. aeruginosa when grown competitively using a cross streak method. Results from TLC-bioautography of the organic extract from Paenibacillus polymyxa will also be discussed.
Comments
The faculty supervisor on this project is Melanie Harvey, Chemistry.