Isolation and Testing of Antibiotics Produced by a Strain of Bacillus subtilis

Location

CoLab, OCB 100

Start Date

27-4-2018 10:30 AM

Document Type

Poster

Description

A close relative of Bacillus subtilis isolated from local soil samples was previously shown to inhibit the growth of E. coli and S. epidermidis when grown competitively using a cross streak method. Organic extracts from this bacteria has been tested against several ESKAPE pathogens using both direct application and TLC–bioautography. Further work to isolate and test the antimicrobial compounds produced by this bacteria closely related to Bacillus subtilis will be discussed. B. subtilis has been found in both soil samples and in the human gastrointestinal tract. It has been widely studied and used. For example, it has been used as an alternative medicine in the treatment of gastrointestinal tract and urinary tract diseases.

Comments

The faculty supervisor for this project was Melanie Harvey, Chemistry.

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Apr 27th, 10:30 AM

Isolation and Testing of Antibiotics Produced by a Strain of Bacillus subtilis

CoLab, OCB 100

A close relative of Bacillus subtilis isolated from local soil samples was previously shown to inhibit the growth of E. coli and S. epidermidis when grown competitively using a cross streak method. Organic extracts from this bacteria has been tested against several ESKAPE pathogens using both direct application and TLC–bioautography. Further work to isolate and test the antimicrobial compounds produced by this bacteria closely related to Bacillus subtilis will be discussed. B. subtilis has been found in both soil samples and in the human gastrointestinal tract. It has been widely studied and used. For example, it has been used as an alternative medicine in the treatment of gastrointestinal tract and urinary tract diseases.