The Search for New Antibiotics

Location

CoLab, OCB 100

Start Date

28-4-2017 1:00 PM

End Date

28-4-2017 2:45 PM

Document Type

Poster

Description

For this project I have been working with several candidates that may be successful in creating a new antibiotic. I have narrowed it down to one candidate and it happens to come from the soil of my own backyard. I have chosen this particular candidate for further research because of its inhibiting characteristics against other organisms. I first noticed the unique characteristics of it when I saw it beginning to grow into a bright orange color. This organism excretes factors that disable pathogens Enterococcus faecalis and Staph epidermis from growing around it. These pathogens were important to screen for inhibition against my candidates because they are safe relatives of the ESKAPE pathogens. The ESKAPE pathogens are the six pathogens that are growing in multidrug resistance and remain a problem in hospitals due to their resistance to antibiotics. Increasing antibiotic resistance makes it harder to treat dangerous infections caused by these pathogens in hospitals, so discovering organisms that could be potential antibiotics is essential. By finding an organism that may prevent the safe relative ESKAPE pathogens from growing, we may be able to discover a new antibiotic.

Comments

The faculty supervisor on this project is Jamie Cunningham, Biology.

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Apr 28th, 1:00 PM Apr 28th, 2:45 PM

The Search for New Antibiotics

CoLab, OCB 100

For this project I have been working with several candidates that may be successful in creating a new antibiotic. I have narrowed it down to one candidate and it happens to come from the soil of my own backyard. I have chosen this particular candidate for further research because of its inhibiting characteristics against other organisms. I first noticed the unique characteristics of it when I saw it beginning to grow into a bright orange color. This organism excretes factors that disable pathogens Enterococcus faecalis and Staph epidermis from growing around it. These pathogens were important to screen for inhibition against my candidates because they are safe relatives of the ESKAPE pathogens. The ESKAPE pathogens are the six pathogens that are growing in multidrug resistance and remain a problem in hospitals due to their resistance to antibiotics. Increasing antibiotic resistance makes it harder to treat dangerous infections caused by these pathogens in hospitals, so discovering organisms that could be potential antibiotics is essential. By finding an organism that may prevent the safe relative ESKAPE pathogens from growing, we may be able to discover a new antibiotic.