Event Title

Towards the Isolation and Identification of Antimicrobial Compounds Produced by Curtobacterium oceanosedimentum and the Initial Screening of Compounds Isolated from Paenibacillus polymyxa.

Location

CoLab, OCB 100

Start Date

28-4-2017 11:00 AM

End Date

28-4-2017 12:45 PM

Document Type

Poster

Description

Curtobacterium oceanosedimentum has been reported to exhibit a range of antimicrobial properties, including the inhibition of several gram-negative and gram-positive bacteria. It was previously shown to inhibit the growth of S. epidermidis when grown competitively using a cross streak method. Organic extracts from Curtobacterium oceanosedimentum showed inhibition towards S. epidermidis in subsequent bioassays using TLC–bioautography. Further work to separate the components in the extract mixture and isolate the antimicrobial compound using both column chromatography and TLC will be discussed. Paenibacillus polymyxa, often used for promotive plant growth in agricultural settings, was previously shown to inhibit the growth of E. aerogenes, S. epidermidis, and P. aeruginosa when grown competitively using a cross streak method. Results from TLC-bioautography of the organic extract from Paenibacillus polymyxa will also be discussed.

Comments

The faculty supervisor on this project is Melanie Harvey, Chemistry.

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Apr 28th, 11:00 AM Apr 28th, 12:45 PM

Towards the Isolation and Identification of Antimicrobial Compounds Produced by Curtobacterium oceanosedimentum and the Initial Screening of Compounds Isolated from Paenibacillus polymyxa.

CoLab, OCB 100

Curtobacterium oceanosedimentum has been reported to exhibit a range of antimicrobial properties, including the inhibition of several gram-negative and gram-positive bacteria. It was previously shown to inhibit the growth of S. epidermidis when grown competitively using a cross streak method. Organic extracts from Curtobacterium oceanosedimentum showed inhibition towards S. epidermidis in subsequent bioassays using TLC–bioautography. Further work to separate the components in the extract mixture and isolate the antimicrobial compound using both column chromatography and TLC will be discussed. Paenibacillus polymyxa, often used for promotive plant growth in agricultural settings, was previously shown to inhibit the growth of E. aerogenes, S. epidermidis, and P. aeruginosa when grown competitively using a cross streak method. Results from TLC-bioautography of the organic extract from Paenibacillus polymyxa will also be discussed.